The tumor suppressor p53 can promote collective cellular migration

Loss of function of the tumor suppressor p53 is known to increase the rate of migration of cells transiting the narrow pores of the traditional Boyden chamber assay. Here by contrast we investigate how p53 impacts the rate of cellular migration within a 2D confluent cell layer and a 3D collagen-embe...

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Vydáno v:PLoS One
Hlavní autoři: He, Shijie, Carman, Christopher V., Lee, Jung Hyun, Lan, Bo, Koehler, Stephan, Atia, Lior, Park, Chan Young, Kim, Jae Hun, Mitchel, Jennifer A., Park, Jin-Ah, Butler, James P., Lu, Quan, Fredberg, Jeffrey J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358060/
https://ncbi.nlm.nih.gov/pubmed/30707705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202065
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