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Functional specificity of a Hox protein mediated by the recognition of minor groove structure

The recognition of specific DNA binding sites by transcription factors is a critical yet poorly understood step in the control of gene expression. Members of the Hox family of transcription factors bind DNA by making nearly identical major groove contacts via the recognition helices of their homeodo...

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Bibliografiset tiedot
Päätekijät: Joshi, Rohit, Passner, Jonathan M., Rohs, Remo, Jain, Rinku, Sosinsky, Alona, Crickmore, Michael A., Jacob, Vinitha, Aggarwal, Aneel K., Honig, Barry, Mann, Richard S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709780/
https://ncbi.nlm.nih.gov/pubmed/17981120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.09.024
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