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Functional specificity of a Hox protein mediated by the recognition of minor groove structure

The recognition of specific DNA binding sites by transcription factors is a critical yet poorly understood step in the control of gene expression. Members of the Hox family of transcription factors bind DNA by making nearly identical major groove contacts via the recognition helices of their homeodo...

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Autors principals: Joshi, Rohit, Passner, Jonathan M., Rohs, Remo, Jain, Rinku, Sosinsky, Alona, Crickmore, Michael A., Jacob, Vinitha, Aggarwal, Aneel K., Honig, Barry, Mann, Richard S.
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709780/
https://ncbi.nlm.nih.gov/pubmed/17981120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.09.024
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