Structural and dynamic characterization of the upper part of the HIV-1 cTAR DNA hairpin

First strand transfer is essential for HIV-1 reverse transcription. During this step, the TAR RNA hairpin anneals to the cTAR DNA hairpin; this annealing reaction is promoted by the nucleocapsid protein and involves an initial loop–loop interaction between the apical loops of TAR and cTAR. Using NMR...

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Autores principales: Zargarian, Loussiné, Kanevsky, Igor, Bazzi, Ali, Boynard, Jonathan, Chaminade, Françoise, Fossé, Philippe, Mauffret, Olivier
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2009
Materias:
Structural Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709575/
https://ncbi.nlm.nih.gov/pubmed/19417069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp297
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