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Specificity of LTR DNA recognition by a peptide mimicking the HIV-1 integrase α4 helix
HIV-1 integrase integrates retroviral DNA through 3′-processing and strand transfer reactions in the presence of a divalent cation (Mg(2+) or Mn(2+)). The α4 helix exposed at the catalytic core surface is essential to the specific recognition of viral DNA. To define group determinants of recognition...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2794180/ https://ncbi.nlm.nih.gov/pubmed/19808934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp824 |
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