Hemoglobin and Its Scavenger Protein Haptoglobin Associate with ApoA-1-containing Particles and Influence the Inflammatory Properties and Function of High Density Lipoprotein

Hemoglobin (Hb) uniquely associates with proinflammatory HDL in atherogenic mice and coronary heart disease (CHD) patients. In this paper, we report that Hb and its scavenger proteins, haptoglobin (Hp) and hemopexin (Hx) are significantly increased in apoA-1-containing particles of HDL both in mouse...

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Autori principali: Watanabe, Junji, Grijalva, Victor, Hama, Susan, Barbour, Karen, Berger, Franklin G., Navab, Mohamad, Fogelman, Alan M., Reddy, Srinivasa T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
Soggetti:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709397/
https://ncbi.nlm.nih.gov/pubmed/19433579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.017202
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