Hemoglobin and Its Scavenger Protein Haptoglobin Associate with ApoA-1-containing Particles and Influence the Inflammatory Properties and Function of High Density Lipoprotein

Hemoglobin (Hb) uniquely associates with proinflammatory HDL in atherogenic mice and coronary heart disease (CHD) patients. In this paper, we report that Hb and its scavenger proteins, haptoglobin (Hp) and hemopexin (Hx) are significantly increased in apoA-1-containing particles of HDL both in mouse...

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Hlavní autoři: Watanabe, Junji, Grijalva, Victor, Hama, Susan, Barbour, Karen, Berger, Franklin G., Navab, Mohamad, Fogelman, Alan M., Reddy, Srinivasa T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709397/
https://ncbi.nlm.nih.gov/pubmed/19433579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.017202
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