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Prostaglandin E(2) Stimulates the Production of Amyloid-β Peptides through Internalization of the EP(4) Receptor
Amyloid-β (Aβ) peptides, generated by the proteolysis of β-amyloid precursor protein by β- and γ-secretases, play an important role in the pathogenesis of Alzheimer disease. Inflammation is also important. We recently reported that prostaglandin E(2) (PGE(2)), a strong inducer of inflammation, stimu...
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| Hoofdauteurs: | , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Biochemistry and Molecular Biology
2009
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709369/ https://ncbi.nlm.nih.gov/pubmed/19407341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.003269 |
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