Prostaglandin E(2) Stimulates the Production of Amyloid-β Peptides through Internalization of the EP(4) Receptor

Amyloid-β (Aβ) peptides, generated by the proteolysis of β-amyloid precursor protein by β- and γ-secretases, play an important role in the pathogenesis of Alzheimer disease. Inflammation is also important. We recently reported that prostaglandin E(2) (PGE(2)), a strong inducer of inflammation, stimu...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Hoshino, Tatsuya, Namba, Takushi, Takehara, Masaya, Nakaya, Tadashi, Sugimoto, Yukihiko, Araki, Wataru, Narumiya, Shuh, Suzuki, Toshiharu, Mizushima, Tohru
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
Soggetti:
Mechanisms of Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709369/
https://ncbi.nlm.nih.gov/pubmed/19407341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.003269
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi