Загрузка...

Prostaglandin E(2) Stimulates the Production of Amyloid-β Peptides through Internalization of the EP(4) Receptor

Amyloid-β (Aβ) peptides, generated by the proteolysis of β-amyloid precursor protein by β- and γ-secretases, play an important role in the pathogenesis of Alzheimer disease. Inflammation is also important. We recently reported that prostaglandin E(2) (PGE(2)), a strong inducer of inflammation, stimu...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Hoshino, Tatsuya, Namba, Takushi, Takehara, Masaya, Nakaya, Tadashi, Sugimoto, Yukihiko, Araki, Wataru, Narumiya, Shuh, Suzuki, Toshiharu, Mizushima, Tohru
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709369/
https://ncbi.nlm.nih.gov/pubmed/19407341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.003269
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!