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Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HIP
Hedgehog (Hh) morphogens play fundamental roles in development whilst dysregulation of Hh signaling leads to disease. Multiple cell surface receptors are responsible for transducing and/or regulating Hh signals. Among these, the hedgehog-interacting protein (HIP) is a highly conserved, vertebrate-sp...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709225/ https://ncbi.nlm.nih.gov/pubmed/19561611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1607 |
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