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A Dual Binding Mode for RhoGTPases in Plexin Signalling
Plexins are cell surface receptors for the semaphorin family of cell guidance cues. The cytoplasmic region comprises a Ras GTPase-activating protein (GAP) domain and a RhoGTPase binding domain. Concomitant binding of extracellular semaphorin and intracellular RhoGTPase triggers GAP activity and sign...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166162/ https://ncbi.nlm.nih.gov/pubmed/21912513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001134 |
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