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Cooperative Effects on Radical Recombination in CYP3A4-Catalyzed Oxidation of the Radical Clock β-Thujone**

The oxidation of hydrocarbons by cytochrome P450 enzymes is commonly thought to involve hydrogen atom abstraction by a ferryl species comparable to that of peroxidase Compound I, followed by radical recombination of the resulting carbon radical with the equivalent of an iron-bound hydroxyl radical.1...

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Bibliografische gegevens
Hoofdauteurs: Jiang, Yongying, Ortiz de Montellano, Paul R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709176/
https://ncbi.nlm.nih.gov/pubmed/19189363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200800772
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