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Cooperative Effects on Radical Recombination in CYP3A4-Catalyzed Oxidation of the Radical Clock β-Thujone**
The oxidation of hydrocarbons by cytochrome P450 enzymes is commonly thought to involve hydrogen atom abstraction by a ferryl species comparable to that of peroxidase Compound I, followed by radical recombination of the resulting carbon radical with the equivalent of an iron-bound hydroxyl radical.1...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709176/ https://ncbi.nlm.nih.gov/pubmed/19189363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200800772 |
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