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An Immunogenic, Surface-Exposed Domain of Haemophilus ducreyi Outer Membrane Protein HgbA Is Involved in Hemoglobin Binding

HgbA is the sole TonB-dependent receptor for hemoglobin (Hb) acquisition of Haemophilus ducreyi. Binding of Hb to HgbA is the initial step in heme acquisition from Hb. To better understand this step, we mutagenized hgbA by deletion of each of the 11 putative surface-exposed loops and expressed each...

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書誌詳細
主要な著者: Nepluev, Igor, Afonina, Galyna, Fusco, William G., Leduc, Isabelle, Olsen, Bonnie, Temple, Brenda, Elkins, Christopher
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708535/
https://ncbi.nlm.nih.gov/pubmed/19451245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00034-09
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