A Class I Haemophilus ducreyi Strain Containing a Class II hgbA Allele Is Partially Attenuated in Humans: Implications for HgbA Vaccine Efficacy Trials

Haemophilus ducreyi causes chancroid and is a major cause of cutaneous ulcers in children. Due to environmental reservoirs, both class I and class II H. ducreyi strains persist in cutaneous ulcer regions of endemicity following mass drug administration of azithromycin, suggesting the need for a vacc...

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Udgivet i:Infect Immun
Main Authors: Leduc, Isabelle, Fortney, Kate R., Janowicz, Diane M., Zwickl, Beth, Ellinger, Sheila, Katz, Barry P., Lin, Huaiying, Dong, Qunfeng, Spinola, Stanley M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589051/
https://ncbi.nlm.nih.gov/pubmed/31036601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00112-19
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