Immunization with the Haemophilus ducreyi Hemoglobin Receptor HgbA Protects against Infection in the Swine Model of Chancroid

The etiologic agent of chancroid is Haemophilus ducreyi. To fulfill its obligate requirement for heme, H. ducreyi uses two TonB-dependent receptors: the hemoglobin receptor (HgbA) and a receptor for free heme (TdhA). Expression of HgbA is necessary for H. ducreyi to survive and initiate disease in a...

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Main Authors: Afonina, Galyna, Leduc, Isabelle, Nepluev, Igor, Jeter, Chrystina, Routh, Patty, Almond, Glen, Orndorff, Paul E., Hobbs, Marcia, Elkins, Christopher
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1418891/
https://ncbi.nlm.nih.gov/pubmed/16552053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.4.2224-2232.2006
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