Immunization with the Haemophilus ducreyi Hemoglobin Receptor HgbA Protects against Infection in the Swine Model of Chancroid

The etiologic agent of chancroid is Haemophilus ducreyi. To fulfill its obligate requirement for heme, H. ducreyi uses two TonB-dependent receptors: the hemoglobin receptor (HgbA) and a receptor for free heme (TdhA). Expression of HgbA is necessary for H. ducreyi to survive and initiate disease in a...

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Detalhes bibliográficos
Main Authors: Afonina, Galyna, Leduc, Isabelle, Nepluev, Igor, Jeter, Chrystina, Routh, Patty, Almond, Glen, Orndorff, Paul E., Hobbs, Marcia, Elkins, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1418891/
https://ncbi.nlm.nih.gov/pubmed/16552053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.4.2224-2232.2006
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