Passive Immunization with a Polyclonal Antiserum to the Hemoglobin Receptor of Haemophilus ducreyi Confers Protection against a Homologous Challenge in the Experimental Swine Model of Chancroid

Haemophilus ducreyi, the etiologic agent of chancroid, has an obligate requirement for heme. Heme is acquired by H. ducreyi from its human host via TonB-dependent transporters expressed at its bacterial surface. Of 3 TonB-dependent transporters encoded in the genome of H. ducreyi, only the hemoglobi...

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Autori principali: Leduc, Isabelle, Fusco, William G., Choudhary, Neelima, Routh, Patty A., Cholon, Deborah M., Hobbs, Marcia M., Almond, Glen W., Orndorff, Paul E., Elkins, Christopher
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147553/
https://ncbi.nlm.nih.gov/pubmed/21646451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00017-11
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