Passive Immunization with a Polyclonal Antiserum to the Hemoglobin Receptor of Haemophilus ducreyi Confers Protection against a Homologous Challenge in the Experimental Swine Model of Chancroid

Haemophilus ducreyi, the etiologic agent of chancroid, has an obligate requirement for heme. Heme is acquired by H. ducreyi from its human host via TonB-dependent transporters expressed at its bacterial surface. Of 3 TonB-dependent transporters encoded in the genome of H. ducreyi, only the hemoglobi...

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Hlavní autoři: Leduc, Isabelle, Fusco, William G., Choudhary, Neelima, Routh, Patty A., Cholon, Deborah M., Hobbs, Marcia M., Almond, Glen W., Orndorff, Paul E., Elkins, Christopher
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147553/
https://ncbi.nlm.nih.gov/pubmed/21646451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00017-11
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