Immunization with the Haemophilus ducreyi Hemoglobin Receptor HgbA with Adjuvant Monophosphoryl Lipid A Protects Swine from a Homologous but Not a Heterologous Challenge

Haemophilus ducreyi, the etiological agent of chancroid, has a strict requirement for heme, which it acquires from its only natural host, humans. Previously, we showed that a vaccine preparation containing the native hemoglobin receptor HgbA purified from H. ducreyi class I strain 35000HP (nHgbA(I))...

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Detalhes bibliográficos
Main Authors: Fusco, William G., Afonina, Galyna, Nepluev, Igor, Cholon, Deborah M., Choudhary, Neelima, Routh, Patricia A., Almond, Glenn W., Orndorff, Paul E., Staats, Herman, Hobbs, Marcia M., Leduc, Isabelle, Elkins, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937461/
https://ncbi.nlm.nih.gov/pubmed/20584974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00217-10
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