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Aneuploidy and Improved Growth Are Coincident but Not Causal in a Yeast Cancer Model

Cancer cells have acquired mutations that alter their growth. Aneuploidy that typify cancer cells are often assumed to contribute to the abnormal growth characteristics. Here we test the idea of a link between aneuploidy and mutations allowing improved growth, using Saccharomyces cerevisiae containi...

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Autors principals: Li, Xin Chenglin, Schimenti, John C., Tye, Bik K.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708349/
https://ncbi.nlm.nih.gov/pubmed/19636358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000161
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