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Aneuploidy and Improved Growth Are Coincident but Not Causal in a Yeast Cancer Model

Cancer cells have acquired mutations that alter their growth. Aneuploidy that typify cancer cells are often assumed to contribute to the abnormal growth characteristics. Here we test the idea of a link between aneuploidy and mutations allowing improved growth, using Saccharomyces cerevisiae containi...

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Detalhes bibliográficos
Main Authors: Li, Xin Chenglin, Schimenti, John C., Tye, Bik K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708349/
https://ncbi.nlm.nih.gov/pubmed/19636358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000161
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