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Ploidy Dictates Repair Pathway Choice under DNA Replication Stress
This study reports an unusual ploidy-specific response to replication stress presented by a defective minichromosome maintenance (MCM) helicase allele in yeast. The corresponding mouse allele, Mcm4(Chaos3), predisposes mice to mammary gland tumors. While mcm4(Chaos3) causes replication stress in bot...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Genetics Society of America
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3070513/ https://ncbi.nlm.nih.gov/pubmed/21242538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.125450 |
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