hERG1a/1b heteromeric currents exhibit amplified attenuation of inactivation in variant 1 short QT syndrome

Potassium channels encoded by hERG (human ether-à-go-go-related gene) underlie the cardiac rapid delayed rectifier K(+) current (I(Kr)) and hERG mutations underpin clinically important repolarization disorders. Virtually all electrophysiological investigations of hERG mutations have studied exclusiv...

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Autors principals: McPate, M.J., Zhang, H., Cordeiro, J.M., Dempsey, C.E., Witchel, H.J., Hancox, J.C.
Format: Artigo
Idioma:Inglês
Publicat: Academic Press 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708341/
https://ncbi.nlm.nih.gov/pubmed/19501051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.05.134
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