Increased Vulnerability of Human Ventricle to Re-entrant Excitation in hERG-linked Variant 1 Short QT Syndrome

The short QT syndrome (SQTS) is a genetically heterogeneous condition characterized by abbreviated QT intervals and an increased susceptibility to arrhythmia and sudden death. This simulation study identifies arrhythmogenic mechanisms in the rapid-delayed rectifier K(+) current (I(Kr))-linked SQT1 v...

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Detalhes bibliográficos
Main Authors: Adeniran, Ismail, McPate, Mark J., Witchel, Harry J., Hancox, Jules C., Zhang, Henggui
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240585/
https://ncbi.nlm.nih.gov/pubmed/22194679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002313
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