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Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant
A specialized class of RNases shows a high cytotoxicity toward tumor cell lines, which is critically dependent on their ability to reach the cytosol and to evade the action of the ribonuclease inhibitor (RI). The cytotoxicity and antitumor activity of bovine seminal ribonuclease (BSRNase), which exi...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2708022/ https://ncbi.nlm.nih.gov/pubmed/19177350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.6 |
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