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Open Interface and Large Quaternary Structure Movements in 3D Domain Swapped Proteins: Insights from Molecular Dynamics Simulations of the C-Terminal Swapped Dimer of Ribonuclease A

Bovine pancreatic ribonuclease (RNase A) forms two three-dimensional (3D) domain swapped dimers. Crystallographic investigations have revealed that these dimers display completely different quaternary structures: one dimer (N-dimer), which presents the swapping of the N-terminal helix, is characteri...

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Detalhes bibliográficos
Main Authors: Merlino, Antonello, Ceruso, Marc Antoine, Vitagliano, Luigi, Mazzarella, Lelio
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305252/
https://ncbi.nlm.nih.gov/pubmed/15596505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.048611
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