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Clathrin-Independent Endocytosis of ErbB2 in Geldanamycin-Treated Human Breast Cancer Cells

The EGF receptor family member ErbB2 in is commonly overexpressed in human breast cancer cells and correlates with poor prognosis. Geldanamycin (GA) induces ErbB2 ubiquitination, intracellular accumulation, and degradation. Whether GA stimulates ErbB2 internalization is controversial. We found that...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Barr, Daniel J., Ostermeyer-Fay, Anne G., Matundan, Rachel A., Brown, Deborah A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707784/
https://ncbi.nlm.nih.gov/pubmed/18765569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.020404
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