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Structural Model for Dihydropyridine Binding to L-type Calcium Channels

1,4-Dihydropyridines (DHPs) constitute a major class of ligands for L-type Ca(2+) channels (LTCC). The DHPs have a boat-like, six-membered ring with an NH group at the stern, an aromatic moiety at the bow, and substituents at the port and starboard sides. Various DHPs exhibit antagonistic or agonist...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Tikhonov, Denis B., Zhorov, Boris S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707233/
https://ncbi.nlm.nih.gov/pubmed/19416978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.011296
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