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Possible Roles of Exceptionally Conserved Residues around the Selectivity Filters of Sodium and Calcium Channels

In the absence of x-ray structures of sodium and calcium channels their homology models are used to rationalize experimental data and design new experiments. A challenge is to model the outer-pore region that folds differently from potassium channels. Here we report a new model of the outer-pore reg...

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Библиографические подробности
Главные авторы: Tikhonov, Denis B., Zhorov, Boris S.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024794/
https://ncbi.nlm.nih.gov/pubmed/21081490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.175406
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