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Conservation and variability of the pore-lining helices in P-loop channels

The family of P-loop channels, which play key roles in the cell physiology, is characterized by four membrane re-entering extracellular P-loops that connect eight transmembrane helices of the pore-forming domain. The X-ray and cryo-EM structures of the open- and closed-state channels show conserved...

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Detalhes bibliográficos
Publicado no:Channels (Austin)
Main Authors: Tikhonov, Denis B., Zhorov, Boris S.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786192/
https://ncbi.nlm.nih.gov/pubmed/29095093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2017.1395536
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