Selectivity filters and cysteine-rich extracellular loops in voltage-gated sodium, calcium, and NALCN channels

How nature discriminates sodium from calcium ions in eukaryotic channels has been difficult to resolve because they contain four homologous, but markedly different repeat domains. We glean clues from analyzing the changing pore region in sodium, calcium and NALCN channels, from single-cell eukaryote...

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Vydáno v:Front Physiol
Hlavní autoři: Stephens, Robert F., Guan, W., Zhorov, Boris S., Spafford, J. David
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436565/
https://ncbi.nlm.nih.gov/pubmed/26042044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2015.00153
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