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Structural Model for Dihydropyridine Binding to L-type Calcium Channels
1,4-Dihydropyridines (DHPs) constitute a major class of ligands for L-type Ca(2+) channels (LTCC). The DHPs have a boat-like, six-membered ring with an NH group at the stern, an aromatic moiety at the bow, and substituents at the port and starboard sides. Various DHPs exhibit antagonistic or agonist...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2707233/ https://ncbi.nlm.nih.gov/pubmed/19416978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.011296 |
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