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Structural Model for Dihydropyridine Binding to L-type Calcium Channels

1,4-Dihydropyridines (DHPs) constitute a major class of ligands for L-type Ca(2+) channels (LTCC). The DHPs have a boat-like, six-membered ring with an NH group at the stern, an aromatic moiety at the bow, and substituents at the port and starboard sides. Various DHPs exhibit antagonistic or agonist...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Tikhonov, Denis B., Zhorov, Boris S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707233/
https://ncbi.nlm.nih.gov/pubmed/19416978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.011296
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