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Functions of Phenylalanine Residues within the β-Barrel Stem of the Anthrax Toxin Pore

BACKGROUND: A key step of anthrax toxin action involves the formation of a protein-translocating pore within the endosomal membrane by the Protective Antigen (PA) moiety. Formation of this transmembrane pore by PA involves interaction of the seven 2β2–2β3 loops of the heptameric precursor to generat...

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Bibliografske podrobnosti
Main Authors: Wang, Jie, Vernier, Gregory, Fischer, Audrey, Collier, R. John
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706995/
https://ncbi.nlm.nih.gov/pubmed/19609431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006280
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