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Effects of Introducing a Single Charged Residue into the Phenylalanine Clamp of Multimeric Anthrax Protective Antigen

Multimeric pores formed in the endosomal membrane by the Protective Antigen moiety of anthrax toxin translocate the enzymatic moieties of the toxin to the cytosolic compartment of mammalian cells. There is evidence that the side chains of the Phe(427) residues come into close proximity with one anot...

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Detalhes bibliográficos
Main Authors: Janowiak, Blythe E., Fischer, Audrey, Collier, R. John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832964/
https://ncbi.nlm.nih.gov/pubmed/20061382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.093195
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