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Solubilization and characterization of the anthrax toxin pore in detergent micelles

Proteolytically activated Protective Antigen (PA) moiety of anthrax toxin self-associates to form a heptameric ring-shaped oligomer (the prepore). Acidic pH within the endosome converts the prepore to a pore that serves as a passageway for the toxin's enzymatic moieties to cross the endosomal m...

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Detalhes bibliográficos
Main Authors: Vernier, Gregory, Wang, Jie, Jennings, Laura D, Sun, Jianjun, Fischer, Audrey, Song, Likai, Collier, R John
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777363/
https://ncbi.nlm.nih.gov/pubmed/19609933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.199
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