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Solubilization and characterization of the anthrax toxin pore in detergent micelles
Proteolytically activated Protective Antigen (PA) moiety of anthrax toxin self-associates to form a heptameric ring-shaped oligomer (the prepore). Acidic pH within the endosome converts the prepore to a pore that serves as a passageway for the toxin's enzymatic moieties to cross the endosomal m...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2777363/ https://ncbi.nlm.nih.gov/pubmed/19609933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.199 |
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