Overexpression of MYC causes p53-dependent G(2) arrest of normal fibroblasts
Overexpression of the proto-oncogene MYC has been implicated in the genesis of diverse human cancers. One explanation for the role of MYC in tumorigenesis has been that this gene might drive cells inappropriately through the division cycle, leading to the relentless proliferation characteristic of t...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2000
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27061/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10962037/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.190327097 |
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