Overexpression of MYC causes p53-dependent G(2) arrest of normal fibroblasts

Overexpression of the proto-oncogene MYC has been implicated in the genesis of diverse human cancers. One explanation for the role of MYC in tumorigenesis has been that this gene might drive cells inappropriately through the division cycle, leading to the relentless proliferation characteristic of t...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Felsher, Dean W., Zetterberg, Anders, Zhu, Jiyue, Tlsty, Thea, Bishop, J. Michael
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27061/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10962037/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.190327097
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