TYROSINE PHOSPHORYLATION OF MYD88 ADAPTER-LIKE (MAL) IS CRITICAL FOR SIGNAL TRANSDUCTION AND BLOCKED IN ENDOTOXIN TOLERANCE

Toll-like receptor (TLR) 4 recognition of lipopolysaccharide (LPS) triggers signalosome assembly among TLR4, sorting (e.g., MyD88-adapter-like, Mal) and signaling (e.g., MyD88) adapters, initiating recruitment and activation of kinases, activation of transcription factors and production of inflammat...

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Detalhes bibliográficos
Main Authors: Piao, Wenji, Song, Chang, Chen, Haiyan, Wahl, Larry M., Fitzgerald, Katherine A., O’Neill, Luke A., Medvedev, Andrei E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705934/
https://ncbi.nlm.nih.gov/pubmed/18070880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707400200
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