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The double-stranded RNA-binding protein, PACT, is required for postnatal anterior pituitary proliferation

PACT is a double-stranded RNA-binding protein that also binds and activates the latent protein kinase, PKR, which plays a major role in cellular antiviral defense in mammals. For evaluating PACT's contribution to the innate immune system, Pact(−/−) mice have been generated; these mice exhibit n...

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Detalhes bibliográficos
Main Authors: Peters, Gregory A., Seachrist, Darcie D., Keri, Ruth A., Sen, Ganes C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705576/
https://ncbi.nlm.nih.gov/pubmed/19541653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900735106
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