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The double-stranded RNA-binding protein, PACT, is required for postnatal anterior pituitary proliferation
PACT is a double-stranded RNA-binding protein that also binds and activates the latent protein kinase, PKR, which plays a major role in cellular antiviral defense in mammals. For evaluating PACT's contribution to the innate immune system, Pact(−/−) mice have been generated; these mice exhibit n...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2705576/ https://ncbi.nlm.nih.gov/pubmed/19541653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900735106 |
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