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Alkoxyalkyl Esters of 9-(S)-(3-Hydroxy-2-Phosphonomethoxypropyl) Adenine Are Potent and Selective Inhibitors of Hepatitis B Virus (HBV) Replication In Vitro and in HBV Transgenic Mice In Vivo

Alkoxyalkyl esters of acyclic nucleoside phosphonates have previously been shown to have increased antiviral activity when they are administered orally in animal models of viral diseases, including lethal infections with vaccinia virus, cowpox virus, ectromelia virus, murine cytomegalovirus, and ade...

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Autori principali: Morrey, John D., Korba, Brent E., Beadle, James R., Wyles, David L., Hostetler, Karl Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704649/
https://ncbi.nlm.nih.gov/pubmed/19398648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00114-09
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