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Alkoxyalkyl Esters of 9-(S)-(3-Hydroxy-2-Phosphonomethoxypropyl) Adenine Are Potent and Selective Inhibitors of Hepatitis B Virus (HBV) Replication In Vitro and in HBV Transgenic Mice In Vivo

Alkoxyalkyl esters of acyclic nucleoside phosphonates have previously been shown to have increased antiviral activity when they are administered orally in animal models of viral diseases, including lethal infections with vaccinia virus, cowpox virus, ectromelia virus, murine cytomegalovirus, and ade...

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Detalhes bibliográficos
Main Authors: Morrey, John D., Korba, Brent E., Beadle, James R., Wyles, David L., Hostetler, Karl Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704649/
https://ncbi.nlm.nih.gov/pubmed/19398648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00114-09
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