Adoptive immunotherapy mediated by ex vivo expanded natural killer T cells against CD1d-expressing lymphoid neoplasms

BACKGROUND: CD1d is a monomorphic antigen presentation molecule expressed in several hematologic malignancies. Alpha-galactosylceramide (α-GalCer) is a glycolipid that can be presented to cytotoxic CD1d-restricted T cells. These reagents represent a potentially powerful tool for cell mediated immuno...

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Bibliographische Detailangaben
Hauptverfasser: Bagnara, Davide, Ibatici, Adalberto, Corselli, Mirko, Sessarego, Nadia, Tenca, Claudya, De Santanna, Amleto, Mazzarello, Andrea, Daga, Antonio, Corvò, Renzo, De Rossi, Giulio, Frassoni, Francesco, Ciccone, Ermanno, Fais, Franco
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2009
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704307/
https://ncbi.nlm.nih.gov/pubmed/19454494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2008.001339
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