Induction and Survival of Binucleated Purkinje Neurons by Selective Damage and Aging

Fusion of bone marrow-derived cells with adult Purkinje cells in the cerebellum gives rise to binucleated Purkinje cells. Whether fusion can be modulated by epigenetic factors and whether fused neurons are stable has remained unclear. Here, we show that in mice and rats, partial ablation of Purkinje...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Magrassi, Lorenzo, Grimaldi, Piercesare, Ibatici, Adalberto, Corselli, Mirko, Ciardelli, Laura, Castello, Sandra, Podestà, Marina, Frassoni, Francesco, Rossi, Ferdinando
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2007
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672639/
https://ncbi.nlm.nih.gov/pubmed/17855603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2539-07.2007
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