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Lifespan of neurons is uncoupled from organismal lifespan

Neurons in mammals do not undergo replicative aging, and, in absence of pathologic conditions, their lifespan is limited only by the maximum lifespan of the organism. Whether neuronal lifespan is determined by the strain-specific lifetime or can be extended beyond this limit is unknown. Here, we tra...

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Hlavní autoři: Magrassi, Lorenzo, Leto, Ketty, Rossi, Ferdinando
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600460/
https://ncbi.nlm.nih.gov/pubmed/23440189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217505110
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