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Lifespan of neurons is uncoupled from organismal lifespan

Neurons in mammals do not undergo replicative aging, and, in absence of pathologic conditions, their lifespan is limited only by the maximum lifespan of the organism. Whether neuronal lifespan is determined by the strain-specific lifetime or can be extended beyond this limit is unknown. Here, we tra...

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Detalhes bibliográficos
Main Authors: Magrassi, Lorenzo, Leto, Ketty, Rossi, Ferdinando
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600460/
https://ncbi.nlm.nih.gov/pubmed/23440189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217505110
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