Inhibitory Receptors CD85j, LAIR-1, and CD152 Down-Regulate Immunoglobulin and Cytokine Production by Human B Lymphocytes

Class switching consists in the substitution of the heavy-chain constant region of immunoglobulin M (IgM) with that of IgG, IgA, or IgE. This enables antibodies to acquire new effector functions that are crucial to combat invading pathogens. Class switching usually requires engagement of CD40 on B c...

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Autori principali: Merlo, Andrea, Tenca, Claudya, Fais, Franco, Battini, Lorenzo, Ciccone, Ermanno, Grossi, Carlo E., Saverino, Daniele
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
Soggetti:
Antibodies and Mediators of Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1151979/
https://ncbi.nlm.nih.gov/pubmed/15939744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.12.6.705-712.2005
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