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Structure of a mutant form of proliferating cell nuclear antigen that blocks translesion DNA synthesis

Proliferating cell nuclear antigen (PCNA) is a homotrimeric protein that functions as a sliding clamp during DNA replication. Several mutant forms of PCNA that block translesion DNA synthesis have been identified in genetic studies in yeast. One such mutant protein (encoded by the rev6-1 allele) is...

詳細記述

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書誌詳細
主要な著者: Freudenthal, Bret D., Ramaswamy, S., Hingorani, Manju M., Washington, M. Todd
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703463/
https://ncbi.nlm.nih.gov/pubmed/19053247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8017762
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