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Structure of a mutant form of proliferating cell nuclear antigen that blocks translesion DNA synthesis

Proliferating cell nuclear antigen (PCNA) is a homotrimeric protein that functions as a sliding clamp during DNA replication. Several mutant forms of PCNA that block translesion DNA synthesis have been identified in genetic studies in yeast. One such mutant protein (encoded by the rev6-1 allele) is...

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מידע ביבליוגרפי
Main Authors: Freudenthal, Bret D., Ramaswamy, S., Hingorani, Manju M., Washington, M. Todd
פורמט: Artigo
שפה:Inglês
יצא לאור: 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703463/
https://ncbi.nlm.nih.gov/pubmed/19053247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8017762
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