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Structure of a mutant form of proliferating cell nuclear antigen that blocks translesion DNA synthesis

Proliferating cell nuclear antigen (PCNA) is a homotrimeric protein that functions as a sliding clamp during DNA replication. Several mutant forms of PCNA that block translesion DNA synthesis have been identified in genetic studies in yeast. One such mutant protein (encoded by the rev6-1 allele) is...

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Autori principali: Freudenthal, Bret D., Ramaswamy, S., Hingorani, Manju M., Washington, M. Todd
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703463/
https://ncbi.nlm.nih.gov/pubmed/19053247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8017762
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