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Impact of Individual Proliferating Cell Nuclear Antigen-DNA Contacts on Clamp Loading and Function on DNA

Ring-shaped clamp proteins encircle DNA and affect the work of many proteins, notably processive replication by DNA polymerases. Crystal structures of clamps show several cationic residues inside the ring, and in a co-crystal of Escherichia coli β clamp-DNA, they directly contact the tilted duplex p...

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Detalles Bibliográficos
Main Authors: Zhou, Yayan, Hingorani, Manju M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471718/
https://ncbi.nlm.nih.gov/pubmed/22902629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.399071
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