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Intrinsic Flexibility of Ubiquitin on Proliferating Cell Nuclear Antigen (PCNA) in Translesion Synthesis

Ubiquitin conjugation provides a crucial signaling role in hundreds of cellular pathways; however, a structural understanding of ubiquitinated substrates is lacking. One important substrate is monoubiquitinated PCNA (PCNA-Ub), which signals for recruitment of damage-tolerant polymerases in the trans...

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Bibliografiska uppgifter
Huvudupphovsmän: Hibbert, Richard G., Sixma, Titia K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493961/
https://ncbi.nlm.nih.gov/pubmed/22989887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.389890
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