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Design and synthesis of a siderophore conjugate as a potent PSMA inhibitor and potential diagnostic agent for prostate cancer

A Siderophore conjugate was designed as a potential PSMA inhibitor and diagnostic agent for prostate cancer. A semi-rigid spacer was incorporated to avoid competitive participation of iron binding by the enzyme inhibitor relative to the siderophore component. Biological test results showed that, eve...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Ding, Pingyu, Helquist, Paul, Miller, Marvin J.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701565/
https://ncbi.nlm.nih.gov/pubmed/18060794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.11.030
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